PLATELET MONOAMINE OXIDASE B IN FAMILY HISTORY POSITIVE AND FAMILY HISTORY NEGATIVE TYPE 1 ALCOHOL-DEPENDENT SUBJECTS
نویسندگان
چکیده
منابع مشابه
Platelet monoamine oxidase activity in alcoholics with and without a family history of alcoholism.
A number of studies point at platelet monoamine oxidase (MAO) activity being reduced in alcoholics with a family history of drinking, this being a possible vulnerability marker for alcoholism. To test this hypothesis, we examined a group of recently detoxified alcoholics with high (n = 25) and low genetic loading for alcoholism (n = 28) and a group of healthy controls (n = 21). Clinical assessm...
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OBJECTIVE This study compares the natural drinking patterns of family history positive and family history negative women during their first semester of college, a transitional period known to coincide with considerable alcohol-related risks. METHOD Seventy-two incoming undergraduate females, approximately half of whom reported a family history of alcohol misuse, completed initial questionnair...
متن کاملA family history of Type 1 alcoholism differentiates alcohol consumption in high cortisol responders to stress
BACKGROUND The differentiation between high and low cortisol responders to stress is of interest in determining the risk factors which may, along with genetic vulnerability, influence alcohol intake. STUDY 1 METHODS Thirty-two healthy volunteers, family history positive to alcoholism (FHP, n = 16) and family history negative (FHN, n = 16) attended two laboratory sessions during which alcoh...
متن کاملAssociation between Alcoholism Family History and Alcohol Screening Scores among Alcohol-dependent Patients
OBJECTIVE Several tests can be used to screen for alcohol dependence (AD), a prevalent disease with a heterogeneous etiology. As some patients with AD have a strong familial tendency in this regard, a family history of alcohol use disorders can affect the outcomes of screening tests and diagnostic evaluations for AD. In this study, we evaluated associations between a family history of alcohol u...
متن کاملBrief screening for family psychiatric history: the family history screen.
BACKGROUND Brief screens to collect lifetime family psychiatric history are useful in clinical practice and for identifying potential families for genetic studies. METHODS The Family History Screen (FHS) collects information on 15 psychiatric disorders and suicidal behavior in informants and their first-degree relatives. Since each question is posed only once about all family members as a gro...
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ژورنال
عنوان ژورنال: Alcohol and Alcoholism
سال: 2002
ISSN: 1464-3502
DOI: 10.1093/alcalc/37.6.577